Dr. Mell serves as Director of the Center for Precision Radiation Medicine and is Chief of UCSD Head and Neck Radiation Oncology. His clinical interests and expertise are in head and neck and gynecologic cancers. He has expertise in medical statistics and clinical trial design and has previously worked for the National Bureau of Economic Research in Palo Alto, California (1995-1997), and the Center for Health Studies in Seattle, Washington (1997-1999).
His research uses novel image-guided technologies to study the effects of radiation therapy on the immune system. He is the Principal Investigator (PI) of multiple clinical trials, including as national PI of the NRG-HN004 and KEYCHAIN trials, which are studying immune checkpoint inhibitors for patients with head and neck cancer. He is also co-PI of the NRG-GY006 trial studying bone marrow sparing chemoradiation for advanced gynecologic cancers. Dr. Mell serves on several national committees including the NRG and NCCN Head and Neck Cancer Committees, the NRG Cervix Committee, and the NIH Radiation Therapy and Biology Study Section. He is also lead editor of the textbook Principles of Clinical Cancer Research.
Outside work, Dr. Mell is a proud father of two sons, Ryan (17) and Elliot (12). He and his wife, Gina were married in Seattle in 1999. He enjoys running, hiking, creative writing, and spending time with family